SCHEMBL31355836

SCHEMBL31355836

O=C1CCN(c2cccc(NCCCCCCC(=O)N3CCCCC3)c2)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 5/20 0.45
▸ CRBN Q96SW2 5/20 0.45
▸ KDR P35968 1/20 0.42
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ACHE P22303 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MAPT P10636 1/20 0.37
▸ MAPK1 P28482 1/20 0.37
▸ HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355824 1.00 DDB1 (0.45) DDB1CRBNKDRMEN1KMT2A
SCHEMBL31356001 0.90 CRBN (0.43) DDB1CRBNSMN1; SMN2MAPTMAPK1
SCHEMBL31485122 0.88 CASP3 (0.47) DDB1CRBNMEN1KMT2AMAPT
SCHEMBL31355828 0.88 DDB1 (0.43) DDB1CRBNACHE
SCHEMBL31355846 0.84 DDB1 (0.48) DDB1CRBNMEN1KMT2A
SCHEMBL31355968 0.84 DDB1 (0.48) DDB1CRBNMEN1KMT2A
SCHEMBL31355960 0.84 DDB1 (0.48) DDB1CRBNMEN1KMT2A
SCHEMBL31485048 0.81 DDB1 (0.43) DDB1CRBN
SCHEMBL31356020 0.80 CRBN (0.43) DDB1CRBNKDRSMN1; SMN2
SCHEMBL31355870 0.80 DDB1 (0.46) DDB1CRBNSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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