SCHEMBL31355972

SCHEMBL31355972

O=C1CCC(Nc2ccc(NCCCCCCCCN3CCCCC3)cc2)C(=O)N1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.55
▸ DDB1 Q16531 18/20 0.55
▸ HDAC3 O15379 1/20 0.42
▸ HDAC1 Q13547 1/20 0.42
▸ HDAC2 Q92769 1/20 0.42
▸ HDAC8 Q9BY41 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355903 1.00 CRBN (0.55) CRBNDDB1HDAC3HDAC1HDAC2
SCHEMBL31356172 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31356217 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31355909 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31356059 0.89 CRBN (0.52) CRBNDDB1HDAC3HDAC1HDAC2
SCHEMBL31356131 0.89 CRBN (0.52) CRBNDDB1HDAC3HDAC1HDAC2
SCHEMBL31355921 0.89 DDB1 (0.52) CRBNDDB1HDAC3HDAC1HDAC2
SCHEMBL31355967 0.85 CRBN (0.45) CRBNDDB1
SCHEMBL31355862 0.85 CRBN (0.45) CRBNDDB1
SCHEMBL31356213 0.83 DDB1 (0.52) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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