SCHEMBL31355862

SCHEMBL31355862

O=C1CCC(c2ccc(NCCCCCCCN3CCCCC3)cc2)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 12/20 0.45
▸ DDB1 Q16531 11/20 0.45
▸ POLB P06746 1/20 0.43
▸ MAOA P21397 6/20 0.41
▸ MAOB P27338 6/20 0.41
▸ GSPT1 P15170 1/20 0.41
▸ HRH3 Q9Y5N1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355967 1.00 CRBN (0.45) CRBNDDB1POLBMAOAMAOB
SCHEMBL31355787 0.90 POLB (0.45) CRBNDDB1POLBMAOAMAOB
SCHEMBL31356000 0.90 POLB (0.45) CRBNDDB1POLBMAOAMAOB
SCHEMBL31355872 0.89 CRBN (0.53) CRBNDDB1POLBGSPT1
SCHEMBL31355940 0.88 CRBN (0.49) CRBNDDB1MAOAMAOBHRH3
SCHEMBL31355931 0.88 CRBN (0.49) CRBNDDB1MAOAMAOBHRH3
SCHEMBL31355809 0.88 CRBN (0.49) CRBNDDB1MAOAMAOBHRH3
SCHEMBL31355972 0.85 CRBN (0.55) CRBNDDB1
SCHEMBL31355903 0.85 CRBN (0.55) CRBNDDB1
SCHEMBL31355844 0.82 CRBN (0.47) CRBNDDB1POLBGSPT1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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