SCHEMBL31356000

SCHEMBL31356000

O=C1CCC(c2ccc(NCCCCCCCCN3CCC(F)(F)CC3)cc2)C(=O)N1

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.45
▸ CRBN Q96SW2 17/20 0.44
▸ DDB1 Q16531 13/20 0.44
▸ GSPT1 P15170 1/20 0.40
▸ SLC6A4 P31645 1/20 0.36
▸ HRH3 Q9Y5N1 1/20 0.36
▸ MAOA P21397 1/20 0.35
▸ MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355787 1.00 POLB (0.45) POLBCRBNDDB1GSPT1SLC6A4
SCHEMBL31355967 0.90 CRBN (0.45) POLBCRBNDDB1GSPT1HRH3
SCHEMBL31355862 0.90 CRBN (0.45) POLBCRBNDDB1GSPT1HRH3
SCHEMBL31355872 0.88 CRBN (0.53) POLBCRBNDDB1GSPT1
SCHEMBL31355910 0.88 CRBN (0.46) CRBNDDB1
SCHEMBL31356064 0.88 CRBN (0.46) CRBNDDB1
SCHEMBL31356059 0.86 CRBN (0.52) CRBNDDB1
SCHEMBL31356131 0.86 CRBN (0.52) CRBNDDB1
SCHEMBL31355924 0.85 CRBN (0.43) CRBNDDB1GSPT1HRH3
SCHEMBL31484981 0.85 CRBN (0.43) CRBNDDB1GSPT1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119768392-A Aryl or heteroaryl substituted glutarimide derivatives and uses thereof 标新生物医药科技(上海)有限公司 2025-04-04 — — CN claimed
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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