SCHEMBL31356012

SCHEMBL31356012

O=C1CCC(Nc2cccc(NCCCCCCCN3CCC(F)(F)CC3)c2)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.52
▸ DDB1 Q16531 19/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31355948 1.00 CRBN (0.52) CRBNDDB1
SCHEMBL31355909 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31356172 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31356217 0.90 CRBN (0.65) CRBNDDB1
SCHEMBL31356131 0.90 CRBN (0.52) CRBNDDB1
SCHEMBL31356059 0.90 CRBN (0.52) CRBNDDB1
SCHEMBL31356199 0.89 DDB1 (0.52) CRBNDDB1
SCHEMBL31355865 0.89 DDB1 (0.52) CRBNDDB1
SCHEMBL31355934 0.86 DDB1 (0.48) CRBNDDB1
SCHEMBL31355910 0.85 CRBN (0.46) CRBNDDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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