SCHEMBL31355865

SCHEMBL31355865

O=C1CCC(Nc2cccc(NCCCCCCCCN3CCOCC3)c2)C(=O)N1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 15/20 0.52
▸ CRBN Q96SW2 15/20 0.52
▸ NPC1 O15118 2/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ RAD52 P43351 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ CRHBP P24387 1/20 0.42
▸ CRHR2 Q13324 1/20 0.42
▸ EPHX2 P34913 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31356199 1.00 DDB1 (0.52) DDB1CRBNNPC1RAB9AMEN1
SCHEMBL31356172 0.90 CRBN (0.65) DDB1CRBN
SCHEMBL31356217 0.90 CRBN (0.65) DDB1CRBN
SCHEMBL31355909 0.90 CRBN (0.65) DDB1CRBN
SCHEMBL31355921 0.90 DDB1 (0.52) DDB1CRBNNPC1RAB9A
SCHEMBL31355948 0.89 CRBN (0.52) DDB1CRBN
SCHEMBL31356012 0.89 CRBN (0.52) DDB1CRBN
SCHEMBL31356053 0.85 DDB1 (0.56) DDB1CRBNNPC1RAB9AMEN1
SCHEMBL31356166 0.85 DDB1 (0.56) DDB1CRBNNPC1RAB9AMEN1
SCHEMBL31355972 0.80 CRBN (0.55) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025026422-A1 ARYL OR HETEROARYL SUBSTITUTED GLUTARIMIDE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2025-02-06 — — WO claimed
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