Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 2/20 | 0.45 |
| ▸ | NEK2 | P51955 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 10/20 | 0.44 |
| ▸ | LATS1 | O95835 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 6/20 | 0.40 |
| ▸ | PIM1 | P11309 | 3/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | GAK | O14976 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | STK10 | O94804 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31356307 | 0.84 | CHUK (0.45) | NEK2CSNK2A1LATS1ABCG2KDM4E | |
| SCHEMBL31485477 | 0.84 | ABCG2 (0.47) | CSNK2A1LATS1ABCG2CDK5DYRK1A | |
| SCHEMBL27171329 | 0.84 | EPHB4 (0.45) | EPHB4NEK2CSNK2A1LATS1PIM1 | |
| SCHEMBL27074292 | 0.84 | CSNK2A1 (0.54) | CSNK2A1CSNK2A2CSNK2BPIM1PIM2 | |
| SCHEMBL26976038 | 0.83 | CSNK2A1 (0.46) | EPHB4NEK2CSNK2A1ABCG2CSNK2A2 | |
| SCHEMBL27199805 | 0.83 | EPHB4 (0.45) | EPHB4NEK2CSNK2A1ABCG2KDM4E | |
| SCHEMBL31356303 | 0.83 | LATS1 (0.56) | CSNK2A1LATS1ABCG2MAPTABCB1 | |
| SCHEMBL31356294 | 0.82 | EPHB4 (0.47) | EPHB4NEK2CSNK2A1KDM4ECSNK2A2 | |
| SCHEMBL31485532 | 0.82 | TNNI3K (0.47) | CSNK2A1LATS1ABCG2KDM4EMAPT | |
| SCHEMBL27074476 | 0.81 | CSNK2A1 (0.46) | EPHB4CSNK2A1LATS1ABCG2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | claimed |
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | King Faisal University (SA) | 2025-04-08 | — | — | US | disclosed |
| US-12168662-B1 | Pyrido[4′,3′:4,5]pyrrolo[2,3-c][2,7]naphthyridines compounds as CK2 inhibitors | King Faisal University (SA) | 2024-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12168662-B1 | Pyrido[4′,3′:4,5]pyrrolo[2,3-c][2,7]naphthyridines compounds as CK2 inhibitors | CKS2, CDK2, PNKP | EPHB4 2962/4885NEK2 75/4885CSNK2A1 10/4885 |
| US-12269826-B1 | 7H-pyrido[4′,3′:4,5]pyrrolo[2,3-c][1,7]naphthyridine compounds as CK2 inhibitors | CKS2, CSNK1G1, CSNK2A3 | EPHB4 3736/4885NEK2 103/4885CSNK2A1 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.