Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.61 |
| ▸ | PPARG | P37231 | 4/20 | 0.61 |
| ▸ | FBP1 | P09467 | 9/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL421202 | 1.00 | PPARA (0.61) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL197882 | 0.85 | PPARA (0.64) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL20730087 | 0.85 | PPARA (0.64) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL23134009 | 0.85 | PPARA (0.45) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL12670824 | 0.84 | PPARA (0.62) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL2916587 | 0.83 | CYP1A2 (0.49) | PPARAPPARGFBP1CYP1A2CYP3A4 | |
| SCHEMBL6091395 | 0.83 | PPARA (0.69) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL4422408 | 0.82 | PPARA (0.68) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL7988059 | 0.82 | PPARA (0.61) | PPARAPPARGFBP1ABCB11CYP1A2 | |
| SCHEMBL655568 | 0.82 | PPARA (0.61) | PPARAPPARGFBP1ABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114846013-B | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-12-20 | — | — | CN | disclosed |