SCHEMBL2916587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4576129	0.86	CYP1A2 (0.41)	CYP1A2MAPTGAARECQLKMT2A
	SCHEMBL30609812	0.86	CYP1A2 (0.41)	CYP1A2MAPTGAARECQLKMT2A
	SCHEMBL31227691	0.83	PPARA (0.54)	CYP1A2MAPTGAARECQLKMT2A
	SCHEMBL3841972	0.83	PPARA (0.54)	CYP1A2MAPTGAARECQLKMT2A
	SCHEMBL13069642	0.83	CES2 (0.49)	MAPTKMT2ALMNASMN1; SMN2MEN1
	SCHEMBL4607275	0.83	CYP3A4 (0.51)	CYP1A2MAPTKMT2APPARGPPARA
	SCHEMBL31357666	0.83	PPARA (0.61)	CYP1A2MAPTLMNAKDM4EPPARG
	SCHEMBL421202	0.83	PPARA (0.61)	CYP1A2MAPTLMNAKDM4EPPARG
	SCHEMBL14122304	0.82	LMNA (0.50)	MAPTGAAKMT2ALMNASMN1; SMN2
	SCHEMBL5738818	0.81	TP53BP1 (0.43)	KMT2APPARGPPARAMEN1FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.