SCHEMBL31358960

SCHEMBL31358960

COc1cc2c(cc1OC)C(Cc1ccccc1Br)NCC2

nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.60
KMT2A Q03164 3/20 0.55
MEN1 O00255 2/20 0.54
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
PKM P14618 1/20 0.52
KDM4C Q9H3R0 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26368493 1.00 BCHE (0.60) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL28640499 0.91 KDM4E (0.65) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL29506712 0.91 KDM4E (0.65) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL9411108 0.89 BCHE (0.64) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL4024598 0.88 KMT2A (0.55) BCHEKMT2AMEN1KDM4C
SCHEMBL4247485 0.83 BCHE (0.58) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL4250735 0.83 BCHE (0.58) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL4247469 0.83 BCHE (0.58) BCHEKMT2AMEN1KDM4EMAPT
SCHEMBL12634232 0.83 BCHE (0.60) BCHEKMT2AKDM4EMAPTKDM4C
Bromide SCHEMBL6181180 0.82 BCHE (0.57) BCHEKMT2AMEN1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119371356-B Nuciferine derivative, and preparation method and application thereof 云南中医药大学 2026-05-19 CN claimed
CN-119371356-A Nuciferine derivative, and preparation method and application thereof 云南中医药大学 2025-01-28 CN claimed
CN-119371356-B Nuciferine derivative, and preparation method and application thereof 云南中医药大学 2026-05-19 CN disclosed
CN-119371356-A Nuciferine derivative, and preparation method and application thereof 云南中医药大学 2025-01-28 CN disclosed