Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | DRD5 | P21918 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506712 | 1.00 | KDM4E (0.65) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL26368493 | 0.91 | BCHE (0.60) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL31358960 | 0.91 | BCHE (0.60) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL3505850 | 0.84 | KDM4E (0.82) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL14692132 | 0.80 | KDM4E (0.85) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL9411108 | 0.80 | BCHE (0.64) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL4024598 | 0.80 | KMT2A (0.55) | MEN1KMT2ABCHE | |
| SCHEMBL10810217 | 0.80 | ADRB2 (0.64) | KDM4EMAPTPKMMEN1KMT2A | |
| Coclaurine SCHEMBL1901279 | 0.79 | KDM4E (1.00) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL11053411 | 0.79 | KDM4E (0.82) | KDM4EMAPTPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416221-B | Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 | 江西中医药大学 | 2022-03-11 | — | — | CN | claimed |
| CN-113416221-A | Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 | 江西中医药大学 | 2021-09-21 | — | — | CN | claimed |
| CN-113416221-B | Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 | 江西中医药大学 | 2022-03-11 | — | — | CN | disclosed |
| CN-113416221-A | Total synthesis method of natural product phenanthrene alkaloid glycoside compound H4 | 江西中医药大学 | 2021-09-21 | — | — | CN | disclosed |