Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.72 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.43 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599903 | 1.00 | ESR2 (0.72) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL25345784 | 0.92 | ESR2 (0.66) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL30260152 | 0.90 | ESR2 (0.64) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL30199372 | 0.90 | ESR2 (0.68) | ESR2NR1H2MAPK1MAPTHDAC1 | |
| SCHEMBL30199587 | 0.90 | ESR2 (0.64) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL23684302 | 0.90 | ESR2 (0.64) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL21470912 | 0.90 | ESR2 (0.64) | ESR2NR1H2MAPK1MAPTCA1 | |
| SCHEMBL23684548 | 0.90 | ESR2 (0.68) | ESR2NR1H2MAPK1MAPTHDAC1 | |
| SCHEMBL8793500 | 0.89 | ESR2 (0.63) | ESR2NR1H2MAPK1CA1CA2 | |
| SCHEMBL30278467 | 0.89 | ESR2 (0.63) | ESR2NR1H2MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119255984-A | Isoquinolinone derivatives, pharmaceutical compositions containing them and their use | 拜西欧斯（北京）生物技术有限公司 | 2025-01-03 | — | — | CN | disclosed |