Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25205472 | 1.00 | CRACR2A (0.45) | CRACR2ARAB9ANPC1KMT2AUBE2T | |
| SCHEMBL22122545 | 0.82 | HDAC3 (0.51) | RAB9AMAPTL3MBTL1KDM4EHDAC3 | |
| SCHEMBL31255121 | 0.78 | CYP1A2 (0.50) | CRACR2AL3MBTL1KDM4EHDAC3HDAC4 | |
| SCHEMBL31255120 | 0.78 | CYP1A2 (0.50) | CRACR2AL3MBTL1KDM4EHDAC3HDAC4 | |
| SCHEMBL22143066 | 0.77 | MAPT (0.44) | KMT2AMAPTMAPK1L3MBTL1KDM4E | |
| SCHEMBL31276280 | 0.76 | STIM1 (0.52) | MAPTMAPK1L3MBTL1KDM4EHDAC3 | |
| SCHEMBL31254635 | 0.76 | KDM5A (0.47) | CRACR2AL3MBTL1KDM4E | |
| SCHEMBL25174562 | 0.76 | STIM1 (0.52) | MAPTMAPK1L3MBTL1KDM4EHDAC3 | |
| SCHEMBL1317978 | 0.75 | MAPK1 (0.59) | RAB9ANPC1KMT2AMAPTMAPK1 | |
| SCHEMBL15750843 | 0.75 | MAPT (0.42) | UBE2TMAPTL3MBTL1KDM4ESTIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119173515-A | Small molecule inhibitors of ubiquitin-specific protease 1 (USP 1) and uses thereof | 英矽智能科技知识产权有限公司 | 2024-12-20 | — | — | CN | disclosed |