Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP1 | O94782 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255079 | 0.82 | PTGS2 (0.54) | RORCPTGS2KDM4EALDH1A1 | |
| SCHEMBL31254731 | 0.79 | USP1 (0.47) | USP1PDE4BPTGS2 | |
| SCHEMBL6391746 | 0.79 | — | — | |
| SCHEMBL1668344 | 0.77 | CRACR2A (0.68) | CRACR2A | |
| SCHEMBL25248159 | 0.77 | USP1 (0.47) | L3MBTL1USP1PDE4BPTGS2KDM4E | |
| SCHEMBL31254979 | 0.77 | KDM4E (0.43) | L3MBTL1USP1PTGS2KDM4EALDH1A1 | |
| SCHEMBL30320380 | 0.77 | USP1 (0.47) | L3MBTL1USP1PDE4BPTGS2KDM4E | |
| SCHEMBL25205472 | 0.76 | CRACR2A (0.45) | CRACR2AL3MBTL1KDM4E | |
| SCHEMBL31359564 | 0.76 | CRACR2A (0.45) | CRACR2AL3MBTL1KDM4E | |
| SCHEMBL25792188 | 0.74 | PTGS2 (0.48) | PDE4BPTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233665-A1 | COMPOUNDS AND THEIR USE AGAINST CANCER | TANGO THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |