Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRPS1 | P60891 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986429 | 0.95 | PRPS1 (0.40) | PRPS1DGAT1MEN1KMT2AGGPS1 | |
| SCHEMBL14502057 | 0.89 | GGPS1 (0.44) | PRPS1DGAT1MEN1KMT2AGGPS1 | |
| SCHEMBL30986474 | 0.84 | MEN1 (0.37) | PRPS1DGAT1MEN1KMT2ABRD4 | |
| SCHEMBL24344409 | 0.83 | MEN1 (0.45) | DGAT1MEN1KMT2AGGPS1FDPS | |
| SCHEMBL15366120 | 0.81 | USP2 (0.40) | DGAT1MEN1KMT2AGGPS1FDPS | |
| SCHEMBL29513592 | 0.81 | MEN1 (0.37) | DGAT1MEN1KMT2ABRD4CREBBP | |
| SCHEMBL24344854 | 0.81 | MEN1 (0.37) | DGAT1MEN1KMT2ABRD4CREBBP | |
| SCHEMBL5951458 | 0.80 | MEN1 (0.56) | MEN1KMT2AGGPS1FDPSNPC1 | |
| SCHEMBL15365942 | 0.79 | USP2 (0.40) | DGAT1MEN1KMT2AGGPS1FDPS | |
| SCHEMBL1271910 | 0.79 | NPC1 (0.41) | DGAT1MEN1KMT2ABRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |