⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361230 | 0.86 | — | — | |
| SCHEMBL31361249 | 0.80 | CHRNB2 (0.32) | — | |
| SCHEMBL31361213 | 0.80 | CHRNB2 (0.32) | — | |
| SCHEMBL31361163 | 0.80 | CHRNB2 (0.32) | — | |
| SCHEMBL31361240 | 0.80 | CHRNB2 (0.32) | — | |
| SCHEMBL31361130 | 0.78 | CHRNB2 (0.30) | — | |
| SCHEMBL31361114 | 0.76 | — | — | |
| SCHEMBL31361235 | 0.67 | NPC1 (0.38) | — | |
| SCHEMBL12024586 | 0.65 | — | — | |
| SCHEMBL31003182 | 0.65 | CHRNB2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746965-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. Hoffmann-La Roche AG (CH) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017041-A1 | BENZIMIDAZOLES AS SIK-ACTIVITY MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-23 | — | — | WO | disclosed |