Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.44 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.41 |
| ▸ | FEN1 | P39748 | 8/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 2/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361279 | 0.84 | ALOX5AP (0.47) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361305 | 0.81 | CYP2C9 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31264718 | 0.79 | CYP2C9 (0.54) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL22658735 | 0.79 | CYP3A4 (0.64) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361271 | 0.78 | FGFR1 (0.60) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361288 | 0.77 | ALOX5AP (0.47) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31361348 | 0.72 | ALOX5AP (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31219423 | 0.71 | CYP3A4 (0.48) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30367018 | 0.69 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL28981128 | 0.69 | ALOX5AP (0.54) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161346-A | Pyrrolo-ring compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2024-12-20 | — | — | CN | disclosed |