SCHEMBL3136136

SCHEMBL3136136

CCOC(=O)CNc1ccc(OC)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.68
MAPT P10636 8/20 0.52
GAA P10253 3/20 0.52
SMN1; SMN2 Q16637 5/20 0.51
KMT2A Q03164 4/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 3/20 0.48
ROCK2 O75116 1/20 0.48
CYP1A2 P05177 2/20 0.48
MAPK1 P28482 1/20 0.48
GLA P06280 1/20 0.48
HTT P42858 1/20 0.47
HPGD P15428 1/20 0.47
MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28492711 0.90 POLB (0.60) POLBMAPTGAASMN1; SMN2KMT2A
SCHEMBL28468875 0.87 POLB (0.68) POLBMAPTGAASMN1; SMN2KMT2A
SCHEMBL9779998 0.86 MAPT (0.59) POLBMAPTGAASMN1; SMN2KMT2A
Hydrochloric Acid SCHEMBL5122021 0.84 MAPT (0.57) POLBMAPTGAASMN1; SMN2KMT2A
SCHEMBL4035087 0.84 POLB (0.65) POLBMAPTGAASMN1; SMN2KMT2A
SCHEMBL6901569 0.84 POLB (0.65) POLBMAPTGAAKMT2AALDH1A1
SCHEMBL3140172 0.84 MAPT (0.58) POLBMAPTGAASMN1; SMN2KMT2A
SCHEMBL28971007 0.83 SMN1; SMN2 (0.63) POLBGAASMN1; SMN2KMT2ANPC1
SCHEMBL1372423 0.83 POLB (0.63) POLBMAPTGAAKMT2ACA12
SCHEMBL28523151 0.83 MAPT (0.55) POLBMAPTGAASMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118151490-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN claimed
CN-118151490-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN claimed
CN-109293568-B Method for synthesizing 3, 4-dihydroquinoline-3 ketone compound by using double-oxidation dehydrocyclization reaction 西北师范大学 2021-01-12 CN claimed
CN-108623547-A A kind of benzo/aphthofurans ketone aryl imine class compound and its synthetic method 湖南大学 2018-10-09 CN claimed
CN-119591512-A Synthesis process of polyfluoro amino acid compound 南京师范大学 2025-03-11 CN disclosed
CN-118151490-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN disclosed
CN-118151490-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN disclosed
CN-117447339-A Method for preparing alkyl substituted glycine derivative by driving visible light 沈阳师范大学 2024-01-26 CN disclosed
CN-116178242-A Preparation method of diindolylmethane alkaloid and derivative thereof catalyzed by recyclable photocatalyst 中国人民解放军海军军医大学 2023-05-30 CN disclosed
CN-113668004-B Method for electrochemical synthesis of non-natural amino acid derivatives 浙江工业大学 2023-05-23 CN disclosed
CN-114890908-B Gamma-trifluoromethyl amino acid derivative and preparation method thereof 华中科技大学 2023-04-21 CN disclosed
CN-115838355-A 1, 4-disubstituted piperazine-2, 5-diketone derivative, preparation method and application thereof 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 2023-03-24 CN disclosed
US-5610299-A Certain aryl substituted imidazopyrazinones; a new class of GABA brain receptor ligands NEUROGEN CORPORATION (US) 1997-03-11 US disclosed
US-5473073-A Useful in diagnosis or treatment of anxiety, sleep and seizure disorders, overdose with bezodiazepine drug and memory enhancement NEUROGEN CORPORATION (US) 1995-12-05 US disclosed
WO-1994015937-A1 CERTAIN ARYL SUBSTITUTED IMIDAZOPYRAZINONES A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1994-07-21 WO disclosed
WO-1993004066-A1 CERTAIN IMIDAZOQUINOXALINOLS; A NEW CLASS OF GABA BRAIN RECEPTOR LIGANDS NEUROGEN CORPORATION (US) 1993-03-04 WO disclosed
US-5182386-A G-Aminobutyric Acid NEUROGEN CORPORATION (US) 1993-01-26 US disclosed
US-4421693-A INSECTICIDES, MITICIDES OR NEMATOCIDES OTSUKA CHEMICAL CO., LTD. (JP) 1983-12-20 US disclosed
US-4413005-A 2,3-DIHYDRO-2,2-DIMETHYLBENZOFURAN-7-YL DERIVATIVES OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) 1983-11-01 US disclosed
US-4250183-A GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1981-02-10 US disclosed