Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.77 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | XDH | P47989 | 2/20 | 0.72 |
| ▸ | FLT3 | P36888 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1104006 | 1.00 | PDGFRB (0.77) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL29368200 | 0.87 | FLT3 (0.67) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL216170 | 0.87 | FLT3 (0.67) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL6866887 | 0.87 | PDGFRB (1.00) | PDGFRBPDGFRAFLT3MEN1CYP1A2 | |
| SCHEMBL2729934 | 0.85 | PDGFRB (0.79) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL335235 | 0.85 | PDGFRB (0.79) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL75327 | 0.85 | KDM4E (1.00) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL16756039 | 0.85 | PDGFRB (0.68) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL6518676 | 0.85 | KDM4E (0.71) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 | |
| SCHEMBL9517979 | 0.84 | PDGFRB (0.72) | PDGFRBPDGFRAKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |