SCHEMBL75327

SCHEMBL75327

CCOC(=O)c1cc2cc(OC)ccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
ALDH1A1 P00352 4/20 1.00
HPGD P15428 3/20 1.00
RAB9A P51151 3/20 1.00
NPC1 O15118 2/20 1.00
LMNA P02545 2/20 1.00
HTT P42858 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
SMN1; SMN2 Q16637 2/20 0.72
HSD17B10 Q99714 1/20 0.72
PDGFRB P09619 2/20 0.68
PDGFRA P16234 2/20 0.68
HRH3 Q9Y5N1 1/20 0.67
MAPT P10636 2/20 0.66
MEN1 O00255 2/20 0.66
KMT2A Q03164 2/20 0.66
GLA P06280 1/20 0.66
GAA P10253 1/20 0.66
ATM Q13315 1/20 0.66
MMP13 P45452 4/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8868735 0.92 RAB9A (0.85) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL5738407 0.89 RAB9A (0.81) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL16756061 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL9263164 0.89 KDM4E (0.80) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL1319990 0.89 RAB9A (0.80) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL5680973 0.86 KDM4E (0.76) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL4815909 0.85 KDM4E (0.74) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL31370745 0.85 KDM4E (0.74) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL1104006 0.85 PDGFRB (0.77) KDM4EALDH1A1HPGDRAB9ANPC1
SCHEMBL31361409 0.85 PDGFRB (0.77) KDM4EALDH1A1HPGDRAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2948454-B1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETI (IN) 2017-05-31 EP claimed
US-9447105-B2 Triazine compounds and a process for preparation thereof COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-09-20 US claimed
US-20150353566-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-10 US claimed
EP-2948454-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF Council of Scientific & Industrial Research An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) 2015-12-02 EP claimed
WO-2014115171-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-07-31 WO claimed
US-20240067639-A1 SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS University of Florida Research Foundation, Incorporation (US) 2024-02-29 US disclosed
US-20240067639-A1 SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS University of Florida Research Foundation, Incorporation (US) 2024-02-29 US disclosed
US-20240067639-A1 SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS University of Florida Research Foundation, Incorporation (US) 2024-02-29 US disclosed
US-20230339915-A1 MODULATORS OF ALPHA-1 ANTITRYPSIN VERTEX PHARMACEUTICALS INCORPORATED 2023-10-26 US disclosed
US-20230339915-A1 MODULATORS OF ALPHA-1 ANTITRYPSIN VERTEX PHARMACEUTICALS INCORPORATED 2023-10-26 US disclosed
US-20230339915-A1 MODULATORS OF ALPHA-1 ANTITRYPSIN VERTEX PHARMACEUTICALS INCORPORATED 2023-10-26 US disclosed
CN-115806570-B Peptoid derivative, pharmaceutical composition and application thereof 南京知和医药科技有限公司 2023-09-12 CN disclosed
US-4269924-A REDUCTION OF INTERIMAGE EFFECTS AND IMPROVED COLOR SEPARATION EFFECTED BY SPECIAL POSITIONING OF THE EMULSION LAYERS TO ACT AS DIFFUSION BARRIERS AGFA-GEVAERT N.V. (BE) 1981-05-26 US disclosed
US-4256831-A FOR COLOR DIFFUSION TRANSFER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-03-17 US disclosed
EP-0024852-A1 2,3-Dihydro-1H-indole derivatives and intermediates therefor, processes for their preparation, pharmaceutical compositions containing these derivatives and their preparation AMERICAN HOME PRODUCTS CORPORATION (US) 1981-03-11 EP disclosed
US-4247629-A FOR DIFFUSION TRANSFER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-01-27 US disclosed
US-4245028-A CONTAINING AN AZO DYE RELEASING REDOX COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1981-01-13 US disclosed
US-4179291-A SILVER HALIDE EMULSION WITH A NON-DIFFUSIBLE DYE PRODUCING COMPOUND AGFA-GEVAERT, A.G. (DE) 1979-12-18 US disclosed
EP-0003376-A1 Photographic material suited for the production of multicolour images by means of diffusion transfer of complexed silver halide AGFA-GEVAERT N.V. (BE) 1979-08-08 EP disclosed
US-4118395-A Method for the production of indolyl lactones FRANTSITS WERNER J 1978-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067639-A1 SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS FUS, SNRPE, RRBP1 KDM4E 1687/4885ALDH1A1 4793/4885HPGD 4750/4885
US-20150353566-A1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF TPH2, IDO2, INMT KDM4E 862/4885ALDH1A1 2885/4885HPGD 2149/4885
US-20230339915-A1 MODULATORS OF ALPHA-1 ANTITRYPSIN SERPINA2, SERPINA3, SERPINB1 KDM4E 4795/4885ALDH1A1 578/4885HPGD 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.