Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570100 | 0.78 | DRD2 (0.45) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL17466611 | 0.77 | DRD2 (0.47) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL12223303 | 0.77 | DRD2 (0.47) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL9966056 | 0.77 | DRD2 (0.47) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL24158896 | 0.75 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2LMNAKDM4ENPC1 | |
| SCHEMBL7983485 | 0.75 | DRD2 (0.45) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL12224868 | 0.75 | DRD2 (0.45) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL1272547 | 0.74 | DRD2 (0.42) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL11037075 | 0.74 | HRH4 (0.42) | DRD2DRD4DRD3HRH4DYRK1A | |
| SCHEMBL3523864 | 0.73 | DRD2 (0.44) | DRD2DRD4DRD3HRH4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |