Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAT2A | P31153 | 2/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361388 | 0.92 | KMT2A (0.42) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361368 | 0.92 | KMT2A (0.42) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361449 | 0.91 | KMT2A (0.40) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361419 | 0.89 | KMT2A (0.41) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361394 | 0.87 | NPSR1 (0.41) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361371 | 0.87 | NPSR1 (0.41) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361424 | 0.86 | NPSR1 (0.41) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361402 | 0.85 | NPSR1 (0.40) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361334 | 0.84 | MAT2A (0.40) | KMT2AMEN1NPSR1HTTSMN1; SMN2 | |
| SCHEMBL31361378 | 0.84 | HTT (0.39) | KMT2AMEN1NPSR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999232-B | MAT2A inhibitors | 南京正大天晴制药有限公司 | 2025-01-07 | — | — | CN | disclosed |