Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.59 |
| ▸ | KDM4B | O94953 | 2/20 | 0.59 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.59 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361480 | 0.91 | ADORA3 (0.61) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL18094474 | 0.86 | SMN1; SMN2 (0.49) | KDM4EMAPTMEN1ALDH1A1HTT | |
| SCHEMBL24107586 | 0.85 | SMN1; SMN2 (0.51) | KDM4EMAPTMEN1HTTKMT2A | |
| SCHEMBL24107632 | 0.82 | ADORA3 (0.69) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL4419709 | 0.80 | TXK (0.47) | KDM4EMAPTMEN1ALDH1A1HTT | |
| SCHEMBL2355543 | 0.79 | LRRK2 (0.67) | KDM4EMAPTMEN1ALDH1A1HTT | |
| SCHEMBL31361531 | 0.79 | ADORA3 (0.67) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL4419707 | 0.78 | HDAC8 (0.49) | KDM4EMAPTMEN1ALDH1A1HTT | |
| SCHEMBL21274054 | 0.78 | MAPT (0.55) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31361538 | 0.77 | ADORA3 (0.64) | ADORA3KDM4AKDM4BKDM5BGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746882-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CeMM - Forschungszentrum für Molekulare Medizin GmbH (AT) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017207-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2025-01-23 | — | — | WO | disclosed |