Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.77 |
| ▸ | KDM4A | O75164 | 3/20 | 0.77 |
| ▸ | KDM4B | O94953 | 3/20 | 0.77 |
| ▸ | KDM5B | Q9UGL1 | 3/20 | 0.77 |
| ▸ | KDM5C | P41229 | 1/20 | 0.71 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.66 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18997293 | 0.87 | GRM1 (0.78) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL17716976 | 0.85 | ADORA3 (0.76) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL18997294 | 0.84 | ADORA3 (0.80) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL18997305 | 0.84 | ADORA3 (0.87) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL19002444 | 0.83 | ADORA3 (0.73) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL18997288 | 0.83 | ADORA3 (0.82) | ADORA3KDM4AKDM4BKDM5BGRM1 | |
| SCHEMBL18997313 | 0.83 | GRM1 (0.80) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL31361484 | 0.82 | ADORA3 (0.90) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL18997311 | 0.81 | ADORA3 (0.79) | ADORA3KDM4AKDM4BKDM5BKDM5C | |
| SCHEMBL18997292 | 0.81 | GRM1 (1.00) | ADORA3KDM4AKDM4BKDM5BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746882-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CeMM - Forschungszentrum für Molekulare Medizin GmbH (AT) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025017207-A1 | INHIBITORS OF SMNDC1 AND THEIR THERAPEUTIC USE | CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) | 2025-01-23 | — | — | WO | disclosed |