Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361688 | 0.96 | RXFP1 (0.46) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361675 | 0.93 | DHODH (0.46) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361585 | 0.90 | PDE4B (0.46) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361656 | 0.88 | PDE4B (0.42) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361690 | 0.87 | KMT2A (0.48) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361695 | 0.87 | AHR (0.43) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361724 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL30962741 | 0.85 | PDE4A (0.43) | PDE4BMAPTPDE4APDE4CPDE4D | |
| SCHEMBL31361632 | 0.85 | PDE4B (0.55) | KMT2AALDH1A1NPSR1RXFP1PDE4B | |
| SCHEMBL31361701 | 0.85 | KMT2A (0.46) | KMT2AALDH1A1NPSR1RXFP1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |