Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20874005 | 0.89 | PDE4B (0.64) | PDE4BMAPTAHRGFER | |
| SCHEMBL31361663 | 0.89 | KMT2A (0.50) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31361724 | 0.88 | KMT2A (0.54) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31361646 | 0.87 | KMT2A (0.50) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31361629 | 0.85 | KMT2A (0.47) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30962730 | 0.85 | POLB (0.46) | PDE4BKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16824917 | 0.85 | RXFP1 (0.55) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31361607 | 0.85 | KMT2A (0.47) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL31361639 | 0.85 | RXFP1 (0.46) | PDE4BRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL30962811 | 0.85 | KMT2A (0.47) | PDE4BRXFP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |