Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31361644 | 1.00 | MAPT (0.42) | MAPTALDH1A1LMNAPOLBEPHA2 | |
| SCHEMBL16652728 | 1.00 | MAPT (0.42) | MAPTALDH1A1LMNAPOLBEPHA2 | |
| SCHEMBL16652730 | 1.00 | MAPT (0.42) | MAPTALDH1A1LMNAPOLBEPHA2 | |
| SCHEMBL16652473 | 0.85 | EPHA2 (0.43) | MAPTLMNAEPHA2ERBB2EPHB4 | |
| SCHEMBL16652472 | 0.85 | EPHA2 (0.43) | MAPTLMNAEPHA2ERBB2EPHB4 | |
| SCHEMBL31361669 | 0.85 | EPHA2 (0.43) | MAPTLMNAEPHA2ERBB2EPHB4 | |
| SCHEMBL16655429 | 0.84 | POLB (0.41) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL16885204 | 0.84 | EPHA2 (0.46) | MAPTLMNAEPHA2ERBB2EPHB4 | |
| SCHEMBL16876582 | 0.84 | EPHA2 (0.46) | MAPTLMNAEPHA2ERBB2EPHB4 | |
| SCHEMBL16876583 | 0.84 | EPHA2 (0.46) | MAPTLMNAEPHA2ERBB2EPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025017116-A1 | PHARMACEUTICAL COMPOUNDS HAVING ACTIVITY AS WEE1 INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2025-01-23 | — | — | WO | disclosed |