Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16652730 | 0.84 | MAPT (0.42) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL16652728 | 0.84 | MAPT (0.42) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31361644 | 0.84 | MAPT (0.42) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31361640 | 0.84 | MAPT (0.42) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL30066325 | 0.82 | ALDH1A1 (0.43) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL31361712 | 0.77 | DRD4 (0.41) | POLBLMNAALDH1A1MAPTKMT2A | |
| SCHEMBL31361681 | 0.77 | ALDH1A1 (0.42) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23764633 | 0.75 | POLB (0.58) | POLBLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL9212935 | 0.75 | POLB (0.58) | POLBLMNASMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3769071 | 0.75 | POLB (0.58) | POLBLMNASMN1; SMN2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015058129-A1 | COMPOSITIONS USEFUL FOR TREATING DISORDERS RELATED TO KIT | BLUEPRINT MEDICINES CORPORATION (US) | 2015-04-23 | — | — | WO | disclosed |