Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | DRD2 | P14416 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11369902 | 1.00 | BCHE (0.46) | BCHEACHENOX1CHEK1CCNB2 | |
| SCHEMBL15502223 | 0.89 | CHEK1 (0.42) | BCHEACHENOX1CHEK1CCNB2 | |
| SCHEMBL29610326 | 0.82 | GAA (0.40) | BCHEACHENOX1CYP1A2CYP3A4 | |
| SCHEMBL342511 | 0.82 | GAA (0.40) | BCHEACHENOX1CYP1A2CYP3A4 | |
| SCHEMBL4709047 | 0.82 | TP53 (0.35) | BCHEACHENOX1CHEK1CES1 | |
| SCHEMBL30771770 | 0.80 | GAA (0.39) | BCHEACHENOX1CYP1A2CYP3A4 | |
| SCHEMBL9004465 | 0.79 | CSNK1G1 (0.42) | NOX1CCNB2CDK1CCNB1GSK3B | |
| SCHEMBL4709361 | 0.75 | TP53 (0.35) | BCHEACHENOX1CHEK1CES1 | |
| SCHEMBL20551035 | 0.75 | NOX1 (0.50) | NOX1CHEK1CCNB2CDK1CCNB1 | |
| SCHEMBL31614597 | 0.73 | GAA (0.43) | NOX1CCNB2CDK1CCNB1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919872-B | Application of tricyclic compound and pharmaceutical composition containing tricyclic compound | 中国药科大学 | 2025-02-07 | — | — | CN | disclosed |