Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29610326 | 0.82 | GAA (0.40) | ACVR1LRRK2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL342511 | 0.82 | GAA (0.40) | ACVR1LRRK2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30771770 | 0.80 | GAA (0.39) | ACVR1LRRK2TDP1KDM4EGAA | |
| SCHEMBL31362086 | 0.79 | BCHE (0.46) | CDK5SMN1; SMN2TDP1MEN1MAPT | |
| SCHEMBL11369902 | 0.79 | BCHE (0.46) | CDK5SMN1; SMN2TDP1MEN1MAPT | |
| SCHEMBL20551035 | 0.78 | NOX1 (0.50) | CDK5RAB9ASMN1; SMN2NPC1TDP1 | |
| SCHEMBL31614597 | 0.73 | GAA (0.43) | CDK5SMN1; SMN2TDP1KDM4EALDH1A1 | |
| SCHEMBL16270632 | 0.72 | CSNK1G1 (0.69) | CSNK1G1CDK5ROS1ACVR1LRRK2 | |
| SCHEMBL15502223 | 0.71 | CHEK1 (0.42) | CDK5LRRK2SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL13833024 | 0.71 | MAPT (0.33) | CDK5LRRK2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500760-A | Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same | DONNELLY CORPORATION (US) | 1996-03-19 | — | — | US | disclosed |
| EP-0531143-A2 | Electrochemichromic solutions, processes for preparing and using the same, and devices manufactured with the same | DONNELLY CORPORATION (US) | 1993-03-10 | — | — | EP | disclosed |