Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16724831 | 0.81 | MAP2K4 (0.39) | ELANEMAP2K4NR1H2UCHL1P2RX3 | |
| SCHEMBL28164583 | 0.80 | MAP2K4 (0.43) | ELANEMAP2K4NR1H2NR1H3UCHL1 | |
| SCHEMBL28298923 | 0.79 | MAP2K4 (0.38) | ELANEMAP2K4NR1H2UCHL1P2RX3 | |
| SCHEMBL25281552 | 0.76 | SMN1; SMN2 (0.42) | ELANEF2PLAUCTRB1MAP2K4 | |
| SCHEMBL185524 | 0.76 | MAP2K4 (0.39) | MAP2K4NR1H2NR1H3JAK1KDM4E | |
| SCHEMBL29793615 | 0.73 | NR1H2 (0.43) | NR1H2NR1H3UCHL1BCHEGPR119 | |
| SCHEMBL28817783 | 0.73 | NR1H2 (0.43) | NR1H2NR1H3UCHL1BCHEGPR119 | |
| SCHEMBL15149187 | 0.71 | NPC1 (0.38) | ELANEMAP2K4KCNH2ALDH1A1 | |
| SCHEMBL30910202 | 0.71 | MAPK13 (0.36) | ELANEF2PLAUCTRB1 | |
| SCHEMBL3668968 | 0.71 | MAP2K4 (0.44) | MAP2K4NR1H2NR1H3UCHL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836054-B | IL4I1 inhibitors and methods of use | 默沙东有限责任公司 | 2024-12-10 | — | — | CN | disclosed |