Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | GPR4 | P46093 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606807 | 0.85 | MAP2K4 (0.40) | MAP2K4L3MBTL1KDM4EALDH1A1NR1H2 | |
| SCHEMBL16724831 | 0.82 | MAP2K4 (0.39) | MAP2K4L3MBTL1KDM4EALDH1A1NR1H2 | |
| SCHEMBL28164583 | 0.81 | MAP2K4 (0.43) | MAP2K4L3MBTL1KDM4EALDH1A1NR1H2 | |
| SCHEMBL12181193 | 0.79 | L3MBTL1 (0.45) | MAP2K4L3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL31362222 | 0.79 | ELANE (0.38) | MAP2K4KDM4EALDH1A1NR1H2UCHL1 | |
| SCHEMBL15149187 | 0.77 | NPC1 (0.38) | MAP2K4L3MBTL1ALDH1A1NPC1HTT | |
| SCHEMBL10967 | 0.75 | PDGFRA (0.44) | MAP2K4FAAHP2RX3ELANE | |
| SCHEMBL14773304 | 0.75 | ELANE (0.43) | MAP2K4ELANE | |
| SCHEMBL29793615 | 0.74 | NR1H2 (0.43) | NR1H2UCHL1CHRM2CHRM4CHRM1 | |
| SCHEMBL28817783 | 0.74 | NR1H2 (0.43) | NR1H2UCHL1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801550-B | Novel chromene kinase modulator | 理森制药股份公司 | 2019-06-14 | — | — | CN | disclosed |