Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10211309 | 0.89 | SPHK1 (0.51) | SPHK1BRD4HSD11B2GLAHCRTR2 | |
| SCHEMBL8445237 | 0.88 | SPHK1 (0.46) | SPHK1BRD4HSD11B2GLAHCRTR2 | |
| SCHEMBL14357932 | 0.88 | SPHK1 (0.46) | SPHK1BRD4HSD11B2GLAHCRTR2 | |
| SCHEMBL31362554 | 0.83 | SPHK1 (0.47) | SPHK1BRD4HSD11B2HCRTR2 | |
| SCHEMBL16545981 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2KDM4E | |
| SCHEMBL17819877 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2KDM4E | |
| SCHEMBL10211186 | 0.83 | SPHK1 (0.49) | SPHK1BRD4HSD11B2HCRTR2KDM4E | |
| SCHEMBL10211328 | 0.82 | SPHK1 (0.54) | SPHK1BRD4HSD11B2GLAHCRTR2 | |
| SCHEMBL11956427 | 0.82 | SPHK1 (0.54) | SPHK1BRD4HSD11B2GLAHCRTR2 | |
| SCHEMBL17244141 | 0.82 | SPHK1 (0.48) | SPHK1BRD4HSD11B2HCRTR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |