Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357932 | 1.00 | SPHK1 (0.46) | SPHK1BRD4HSD11B2ALDH1A1GLA | |
| SCHEMBL31362264 | 0.88 | SPHK1 (0.47) | SPHK1BRD4HSD11B2ALDH1A1GLA | |
| SCHEMBL2326706 | 0.88 | SPHK1 (0.45) | SPHK1BRD4HSD11B2TSHRHCRTR2 | |
| SCHEMBL2326704 | 0.88 | SPHK1 (0.45) | SPHK1BRD4HSD11B2TSHRHCRTR2 | |
| SCHEMBL6918603 | 0.88 | SPHK1 (0.45) | SPHK1BRD4HSD11B2TSHRHCRTR2 | |
| SCHEMBL13964493 | 0.86 | SPHK1 (0.47) | SPHK1BRD4HSD11B2HCRTR2RECQL | |
| SCHEMBL30484737 | 0.86 | SPHK1 (0.47) | SPHK1BRD4HSD11B2HCRTR2RECQL | |
| SCHEMBL7503893 | 0.85 | SPHK1 (0.43) | SPHK1BRD4HSD11B2ALDH1A1GLA | |
| SCHEMBL7506014 | 0.85 | SPHK1 (0.43) | SPHK1BRD4HSD11B2ALDH1A1GLA | |
| SCHEMBL2328925 | 0.85 | SPHK1 (0.46) | SPHK1BRD4HSD11B2HCRTR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026087635-A1 | DIHYDRO BENZOXAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2026-04-30 | — | — | WO | disclosed |
| EP-0656345-B1 | Aspartic acid derivatives or homologues thereof and their use in the treatment of neurological diseases | UNIV PASTEUR (FR) | 1999-03-10 | — | — | EP | disclosed |
| US-5739164-A | BLOCK METABOTROPIC GLUTAMATE RECEPTORS | ELI LILLY AND COMPANY (US) | 1998-04-14 | — | — | US | disclosed |
| US-5589501-A | TREATMENT OF NEUROLOGICAL DISEASES, ANTIPSYCHOTIC, ANTICONVULSANT, ANALGESIC AND ANTIEMETIC AGENT | ELI LILLY AND COMPANY (US) | 1996-12-31 | — | — | US | disclosed |
| EP-0656345-A1 | Aspartic acid derivatives or homologues thereof and their use in the treatment of neurological diseases | Université Louis Pasteur (FR) | 1995-06-07 | — | — | EP | disclosed |