Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30096643 | 0.96 | ATM (0.43) | ATMHDAC4HDAC1CTSKCTSS | |
| SCHEMBL28523987 | 0.96 | ATM (0.43) | ATMHDAC4HDAC1CTSKCTSS | |
| SCHEMBL31028245 | 0.96 | ATM (0.43) | ATMHDAC4HDAC1CTSKCTSS | |
| SCHEMBL28523692 | 0.91 | ATM (0.45) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL30096601 | 0.91 | ATM (0.45) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL31362303 | 0.87 | ATM (0.42) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL31362373 | 0.86 | PPARA (0.41) | ATMCTSKCTSSCTSLCTSB | |
| SCHEMBL20562067 | 0.86 | ALDH1A1 (0.50) | HDAC4HDAC1CTSKHDAC3HDAC7 | |
| SCHEMBL20562065 | 0.86 | ALDH1A1 (0.50) | HDAC4HDAC1CTSKHDAC3HDAC7 | |
| SCHEMBL31028265 | 0.85 | PPARA (0.42) | ATMCTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034858-A1 | FUSED PYRIDINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |