Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | CCNC | P24863 | 2/20 | 0.48 |
| ▸ | CDK8 | P49336 | 2/20 | 0.48 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.48 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17203049 | 1.00 | IRAK4 (0.50) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL30124969 | 0.79 | IRAK4 (0.50) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL22549000 | 0.79 | IRAK4 (0.50) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL17660499 | 0.79 | MAP4K4 (0.77) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL5766404 | 0.79 | IRAK4 (0.50) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL29843629 | 0.75 | SLC22A12 (0.51) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL1147915 | 0.75 | SLC22A12 (0.51) | IRAK4MAP4K4CCNCCDK8CDKN1A | |
| SCHEMBL1192531 | 0.75 | PARP1 (0.47) | MAP4K4ALDH1A1ABCG2 | |
| SCHEMBL30317618 | 0.75 | PARP1 (0.47) | MAP4K4ALDH1A1ABCG2 | |
| SCHEMBL23945884 | 0.75 | IRAK4 (0.60) | IRAK4MAP4K4CCNCCDK8CDKN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119421877-A | Substituted heterocyclic compounds as HSET inhibitors | 默克专利股份公司 | 2025-02-11 | — | — | CN | disclosed |