Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362979 | 1.00 | TIPARP (0.36) | TIPARPDGAT1 | |
| SCHEMBL31362887 | 0.92 | TIPARP (0.35) | TIPARPDGAT1 | |
| SCHEMBL31362907 | 0.91 | TIPARP (0.34) | TIPARPDGAT1 | |
| SCHEMBL25320611 | 0.90 | TIPARP (0.34) | TIPARPDGAT1 | |
| SCHEMBL25320614 | 0.90 | TIPARP (0.34) | TIPARPDGAT1 | |
| SCHEMBL31389000 | 0.89 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL31362913 | 0.88 | TIPARP (0.43) | TIPARPDGAT1 | |
| SCHEMBL31388940 | 0.87 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL31362994 | 0.85 | TIPARP (0.41) | TIPARPDGAT1 | |
| SCHEMBL31363024 | 0.85 | TIPARP (0.41) | TIPARPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066328-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. | 2025-02-27 | — | — | US | disclosed |
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250066328-A1 | PARP7 INHIBITORS | PARP1, PARP2, PARP8 | TIPARP 524/4885DGAT1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.