Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3126421 | 1.00 | USP2 (0.40) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL16893296 | 1.00 | USP2 (0.40) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3137077 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL16893292 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3126287 | 0.84 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL30738928 | 0.82 | NR1H2 (0.45) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL21279710 | 0.77 | USP2 (0.47) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3136479 | 0.77 | NR1H2 (0.39) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3811137 | 0.77 | NR1H2 (0.39) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3135963 | 0.77 | NR1H2 (0.39) | USP2SMN1; SMN2NR1H2RECQLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010056633-A2 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2010-05-20 | — | — | WO | disclosed |
| US-20090156577-A1 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156577-A1 | 7-AMINO ALKYLIDENYL-HETEROCYCLIC QUINOLONES AND NAPHTHYRIDONES | NQO2, QRFPR, NQO1 | USP2 4365/4885SMN1; SMN2 4655/4885NR1H2 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.