Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 5/20 | 0.39 |
| ▸ | PRKACG | P22612 | 4/20 | 0.39 |
| ▸ | PRKACB | P22694 | 4/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 6/20 | 0.36 |
| ▸ | TNKS | O95271 | 5/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.36 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.36 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.36 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30637813 | 0.84 | PARP1 (0.43) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL31363035 | 0.79 | TNKS (0.39) | ADORA2APARP1TNKSTNKS2ROCK2 | |
| SCHEMBL31363032 | 0.79 | ADORA2A (0.45) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL31058281 | 0.73 | PARP1 (0.45) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL31402076 | 0.71 | PRKACA (0.54) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL1690515 | 0.70 | PARP1 (0.48) | PRKACAGRM5PARP1ROCK1ROCK2 | |
| SCHEMBL31718115 | 0.69 | PIM1 (0.42) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL31718095 | 0.68 | ADORA2A (0.45) | ADORA2AHPGDPRKACAPRKACGPRKACB | |
| SCHEMBL12663940 | 0.68 | ROCK2 (0.45) | HPGDPRKACAGRM5PARP1ROCK1 | |
| SCHEMBL25290996 | 0.67 | GRM5 (0.59) | PRKACAPRKACGPRKACBGRM5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025024663-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-01-30 | — | — | WO | disclosed |