SCHEMBL31363

SCHEMBL31363

CCCCC(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)(C(=O)OC1CC(C)(C)NC(C)(C)C1)C(=O)OC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
TSHR P16473 3/20 0.36
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPK1 P28482 2/20 0.36
BLM P54132 2/20 0.36
ATM Q13315 2/20 0.36
HIF1A Q16665 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MAPT P10636 2/20 0.36
USP2 O75604 1/20 0.36
CYP2D6 P10635 1/20 0.36
GAA P10253 8/20 0.36
LMNA P02545 3/20 0.34
GMNN O75496 1/20 0.34
GABBR2 O75899 1/20 0.34
TP53 P04637 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12897908 0.97 KMT2A (0.35) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL14125236 0.95 GAA (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL24107365 0.94 GAA (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL12897904 0.94 GAA (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL5819786 0.93 KMT2A (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL14093368 0.92 GAA (0.32) GAAHMGCR
SCHEMBL13599604 0.91 GAA (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL11498603 0.91 GAA (0.33) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL12672501 0.91 GAA (0.30) ALDH1A1KMT2AMEN1TSHRCYP1A2
SCHEMBL13599657 0.91 EZH2 (0.35) ALDH1A1KMT2AMEN1TSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8668850-B2 Flame-retarded foamed plastic compositions and shaped articles DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 2014-03-11 US claimed
EP-3608366-B1 THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES (JP) 2024-03-06 EP disclosed
EP-3647367-B1 THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TORAY INDUSTRIES (JP) 2023-11-15 EP disclosed
US-11345780-B2 Thermoplastic polyester resin composition and molded article TORAY INDUSTRIES, INC. (JP) 2022-05-31 US disclosed
US-11319437-B2 Thermoplastic polyester resin composition and molded article TORAY INDUSTRIES, INC. (JP) 2022-05-03 US disclosed
US-10913897-B2 Compounds and liquid-crystalline medium MERCK PATENT GMBH (DE) 2021-02-09 US disclosed
US-20210032402-A1 THERMOPLASTIC POLYESTER RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES, INC. (JP) 2021-02-04 US disclosed
US-10907100-B2 Compounds and liquid-crystalline medium MERCK PATENT GMBH (DE) 2021-02-02 US disclosed
EP-3623451-B1 COMPOUND MERCK PATENT GMBH (DE) 2021-01-20 EP disclosed
EP-3354710-B1 COMPOUNDS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
EP-0003809-B1 COPOLYETHERESTER COMPOSITIONS STABILIZED AGAINST OXIDATIVE DEGRADATION AND PROCESS FOR THEIR MANUFACTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-13 EP disclosed
EP-0007468-B1 COMPOSITIONS PHOTODURCISSABLES CIBA-GEIGY AG (CH) 1982-04-07 EP disclosed
US-4284485-A STABILIZED WITH A POLYALKYLPIPERIDINE DERIVATIVE CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
US-4279720-A PHENYLGLYOXYLATE PHOTOINITIATOR WITH POLYALKYLPIPERIDINE STABILIZER CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
EP-0007059-B1 PHOTOCURABLE COMPOSITIONS CIBA-GEIGY AG (CH) 1981-04-15 EP disclosed
US-4198334-A HEAT, LIGHT, OXIDATION RESISTANCE, PLASTICS CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed
EP-0007736-A1 Polyolefin articles sterilisable by gamma-irradiation IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-02-06 EP disclosed
EP-0007059-A1 Photocurable compositions CIBA-GEIGY AG (CH) 1980-01-23 EP disclosed
US-4185003-A PHENOLIC ANTIOXIDANT, HINDERED TETRAMETHYLPIPERIDINE ESTER PHOTOSTABILIZER E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-01-22 US disclosed
EP-0003809-A1 Copolyetherester compositions stabilized against oxidative degradation and process for their manufacture E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10913897-B2 Compounds and liquid-crystalline medium VIM, NEFM, AQP1 ALDH1A1 3572/4885KMT2A 4009/4885MEN1 545/4885
US-10907100-B2 Compounds and liquid-crystalline medium VIM, NEFM, AQP1 ALDH1A1 3505/4885KMT2A 3990/4885MEN1 580/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.