SCHEMBL31363064

SCHEMBL31363064

CC(C)(C)n1nnc(Oc2cccc(Cl)c2)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HAO1 Q9UJM8 1/20 0.42
MGLL Q99685 1/20 0.41
LMNA P02545 2/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
PTGER4 P35408 1/20 0.39
F10 P00742 1/20 0.38
POLB P06746 1/20 0.38
EGFR P00533 1/20 0.38
P2RX4 Q99571 1/20 0.38
PPARG P37231 3/20 0.38
PKM P14618 1/20 0.38
HCAR3 P49019 1/20 0.38
OGG1 O15527 1/20 0.38
XDH P47989 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31362930 0.92 CYP1A2 (0.41) CYP1A2CYP2C9CYP2C19HAO1MGLL
SCHEMBL31363006 0.83 PPARG (0.50) CYP1A2CYP2C9CYP2C19PPARGSMN1; SMN2
SCHEMBL31362939 0.77 AR (0.41) CYP1A2CYP2C9CYP2C19MGLLLMNA
SCHEMBL31362966 0.70 ATM (0.47) CYP1A2CYP2C9CYP2C19PTGER4PPARG
SCHEMBL30424508 0.69 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19HAO1LMNA
SCHEMBL30161820 0.68 HAO1 (0.45) CYP1A2CYP2C9CYP2C19HAO1LMNA
SCHEMBL31719634 0.68 PPARG (0.50) CYP1A2CYP2C9CYP2C19LMNAPTGER4
SCHEMBL24053596 0.68 CSNK2A2 (0.46) CYP1A2CYP2C9CYP2C19HAO1LMNA
SCHEMBL30419536 0.68 CSNK2A2 (0.46) CYP1A2CYP2C9CYP2C19HAO1LMNA
SCHEMBL22608803 0.66 ALDH1A1 (0.40) CYP1A2CYP2C9CYP2C19HAO1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025033011-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2025-02-13 WO disclosed