Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9178074 | 0.92 | KDM4E (0.44) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL17802200 | 0.81 | MAPT (0.36) | KDM4EMAPTALDH1A1PARP1 | |
| SCHEMBL9471242 | 0.79 | AKR1C3 (0.42) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL9179945 | 0.75 | KDM4E (0.55) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL9470708 | 0.74 | MAPT (0.43) | MAPTALDH1A1ADRA2APNMTMAOB | |
| SCHEMBL3945745 | 0.73 | KDM4E (0.43) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL3949652 | 0.73 | KDM4E (0.43) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL3950860 | 0.73 | KDM4E (0.43) | KDM4EDYRK1AMAPTALDH1A1HPGD | |
| SCHEMBL9175444 | 0.73 | KDM4E (0.43) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 | |
| SCHEMBL4035775 | 0.73 | KDM4E (0.43) | KDM4EMAPK8CSNK1A1LIMK1PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |