Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177580 | 0.91 | MAPT (0.41) | MAPTADRA2APNMTALDH1A1HSP90AA1 | |
| SCHEMBL9471345 | 0.90 | MAPT (0.40) | MAPTADRA2APNMTALDH1A1HSP90AA1 | |
| SCHEMBL3899701 | 0.78 | CTSL (0.49) | MAPTADRA2APNMTALDH1A1MAPK1 | |
| SCHEMBL3925257 | 0.76 | HTR1D (0.44) | MAPTADRA2APNMTALDH1A1MAPK1 | |
| SCHEMBL3506059 | 0.76 | ALDH1A1 (0.48) | MAPTADRA2APNMTALDH1A1MAPK1 | |
| SCHEMBL10180113 | 0.76 | ADRA2A (0.44) | MAPTADRA2APNMTALDH1A1TDP1 | |
| SCHEMBL14159974 | 0.76 | LMNA (0.46) | MAPTADRA2APNMTALDH1A1MAPK1 | |
| SCHEMBL3920383 | 0.76 | ALDH1A1 (0.50) | MAPTADRA2APNMTALDH1A1HSP90AA1 | |
| SCHEMBL9173956 | 0.75 | KMT2A (0.41) | MAPTALDH1A1MAPK1SMN1; SMN2CYP3A4 | |
| SCHEMBL9471242 | 0.74 | AKR1C3 (0.42) | MAPTPNMTALDH1A1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242912-A | Treatment of autoimmune and rheumatic diseases and osteoporosis | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| EP-0434844-A1 | NEW CYCLIC ANTHRANILIC ACID DERIVATIVE AND METHOD OF PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |