Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25907603 | 0.85 | CYP17A1 (0.37) | BRD9CYP17A1AAK1RXFP1METAP1 | |
| SCHEMBL30050908 | 0.85 | AAK1 (0.36) | BRD9CYP17A1AAK1RXFP1METAP1 | |
| SCHEMBL24822119 | 0.85 | AAK1 (0.36) | BRD9CYP17A1AAK1RXFP1METAP1 | |
| SCHEMBL31304965 | 0.82 | GPR119 (0.32) | BRD9CYP17A1AAK1RXFP1METAP1 | |
| SCHEMBL29208185 | 0.82 | ATR (0.42) | BRD9AAK1RXFP1POLBGAA | |
| SCHEMBL31304930 | 0.81 | RXFP1 (0.33) | BRD9CYP17A1AAK1RXFP1METAP1 | |
| SCHEMBL25909101 | 0.80 | CYP17A1 (0.37) | BRD9CYP17A1RXFP1METAP1CA12 | |
| SCHEMBL30050648 | 0.78 | AAK1 (0.38) | BRD9AAK1KCNQ4KCNQ5LMNA | |
| SCHEMBL24822117 | 0.78 | AAK1 (0.38) | BRD9AAK1KCNQ4KCNQ5LMNA | |
| SCHEMBL25909307 | 0.77 | GAA (0.39) | CYP17A1AAK1RXFP1METAP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |