Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 9/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634932 | 0.83 | CYP17A1 (0.48) | CYP17A1CYP1A2AREGLN1 | |
| SCHEMBL1290332 | 0.78 | PARP1 (0.47) | PARP1L3MBTL1AURKARPS6KB1AURKB | |
| SCHEMBL30119632 | 0.78 | CYP17A1 (0.60) | CYP17A1CYP1A2ARL3MBTL1 | |
| SCHEMBL29829828 | 0.76 | HTT (0.54) | PARP1PARP2PARP3AURKARPS6KB1 | |
| SCHEMBL21555726 | 0.75 | CYP17A1 (0.54) | CYP17A1CYP1A2AR | |
| SCHEMBL28625938 | 0.75 | CYP17A1 (0.51) | CYP17A1CYP1A2AR | |
| SCHEMBL30098925 | 0.74 | IDO1 (0.44) | L3MBTL1 | |
| SCHEMBL16497015 | 0.74 | PARP1 (0.49) | PARP1PARP2L3MBTL1PARP3AURKA | |
| SCHEMBL29830638 | 0.74 | ADRA1D (0.48) | PARP1PARP2PARP3AURKARPS6KB1 | |
| SCHEMBL27249587 | 0.73 | PARP1 (0.47) | PARP1L3MBTL1AURKARPS6KB1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |