Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29397449 | 0.82 | NR4A2 (0.44) | PARP1CD38AXLNR4A2MAP2K1 | |
| SCHEMBL18225293 | 0.82 | NR4A2 (0.48) | NR4A2 | |
| SCHEMBL22443320 | 0.82 | NR4A2 (0.44) | PARP1NR4A2 | |
| SCHEMBL22470597 | 0.82 | NR4A2 (0.44) | PARP1CD38AXLNR4A2MAP2K1 | |
| SCHEMBL15808776 | 0.82 | PARP1 (0.42) | PARP1CD38 | |
| SCHEMBL667272 | 0.81 | BCL2 (0.47) | PARP1AXLMAP2K1 | |
| SCHEMBL12999419 | 0.77 | CYP3A4 (0.46) | — | |
| SCHEMBL2720949 | 0.76 | KMT2A (0.42) | CREBBP | |
| SCHEMBL536589 | 0.75 | PARP1 (0.64) | PARP1NR4A2CREBBP | |
| SCHEMBL27185965 | 0.75 | JAK2 (0.43) | PARP1CD38AXLNR4A2MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |