Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4241671 | 1.00 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL8626579 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAHPGDNPSR1 | |
| SCHEMBL23144086 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL29811691 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL15828734 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TDP1LMNAL3MBTL1HPGD | |
| SCHEMBL2815324 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL2946298 | 0.83 | CHEK1 (0.50) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL2946295 | 0.83 | CHEK1 (0.50) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL14141587 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TDP1LMNASIRT6L3MBTL1 | |
| SCHEMBL15456899 | 0.82 | CHEK1 (0.49) | ALDH1A1TDP1LMNASIRT6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025059074-A1 | BICYCLIC COMPOUNDS FOR RESTORING MUTANT P53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2025-03-20 | — | — | WO | disclosed |