SCHEMBL31364059

SCHEMBL31364059

O=Cc1cccc(-c2ccccc2)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.55
HDAC4 P56524 1/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
HDAC6 Q9UBN7 1/20 0.53
HNF4A P41235 1/20 0.53
TRIM24 O15164 1/20 0.48
TRIM33 Q9UPN9 1/20 0.48
TLR2 O60603 1/20 0.47
TLR1 Q15399 1/20 0.47
TLR6 Q9Y2C9 1/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
BCL2L1 Q07817 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1043113 1.00 ERN1 (0.55) ERN1HDAC4HDAC2HDAC8HDAC6
2-Phenylphenol SCHEMBL11562842 0.93 ALDH1A1 (0.59) ERN1HDAC4HDAC2HDAC8HDAC6
SCHEMBL7091474 0.87 CNR2 (0.47) ERN1HDAC4HDAC2HDAC8HDAC6
SCHEMBL16439936 0.85 ERN1 (0.67) ERN1TRIM24TRIM33TLR2TLR1
SCHEMBL31152506 0.85 ERN1 (0.67) ERN1TRIM24TRIM33TLR2TLR1
SCHEMBL7009289 0.84 HDAC4 (0.48) ERN1HDAC4HDAC2HDAC8HDAC6
SCHEMBL2561443 0.84 ERN1 (0.53) ERN1HNF4ATRIM24TRIM33TLR2
SCHEMBL1423844 0.83 ERN1 (0.50) ERN1HDAC4HDAC2HDAC8HDAC6
SCHEMBL5735298 0.83 ERN1 (0.52) ERN1TRIM24TRIM33TLR2TLR1
SCHEMBL2560945 0.83 ERN1 (0.50) ERN1HDAC4HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119176807-A Alpha-hydroxy ketone nitrogen-containing fused ring compound and application thereof 北京英飞智药科技有限公司 2024-12-24 CN disclosed