Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364102 | 0.69 | HTT (0.47) | EGLN1 | |
| SCHEMBL31363913 | 0.57 | EGLN1 (0.40) | EGLN1KDM4EKDM6AKDM4ACYP2C9 | |
| SCHEMBL2270859 | 0.54 | — | — | |
| SCHEMBL15264650 | 0.54 | KDM4E (0.45) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL31022844 | 0.54 | KDM4E (0.45) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL4549933 | 0.52 | KDM4E (0.57) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL15966900 | 0.52 | PDE3B (0.35) | EGLN1 | |
| Hydrochloric Acid SCHEMBL31516277 | 0.52 | EGLN1 (0.39) | EGLN1 | |
| Deferiprone SCHEMBL94474 | 0.52 | KDM4E (1.00) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 | |
| SCHEMBL18117860 | 0.51 | KDM4E (0.60) | KDM4EKDM6AKDM4ACYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176807-A | Alpha-hydroxy ketone nitrogen-containing fused ring compound and application thereof | 北京英飞智药科技有限公司 | 2024-12-24 | — | — | CN | disclosed |