Deferiprone

Deferiprone

SCHEMBL94474

Cc1c(O)c(=O)ccn1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 1.00
CYP2C19 P33261 2/20 1.00
KDM6A O15550 1/20 1.00
KDM4A O75164 1/20 1.00
CYP2C9 P11712 1/20 1.00
KDM5C P41229 1/20 1.00
KDM2B Q8NHM5 1/20 1.00
DOHH Q9BU89 1/20 1.00
KDM2A Q9Y2K7 1/20 1.00
COMT P21964 2/20 0.53
HTT P42858 2/20 0.49
TP53 P04637 1/20 0.49
CYP2D6 P10635 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
APP P05067 3/20 0.42
HRH3 Q9Y5N1 3/20 0.42
LMNA P02545 1/20 0.39
MMP1 P03956 1/20 0.38
MMP7 P09237 1/20 0.38
MMP9 P14780 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deferiprone SCHEMBL20775057 1.00 KDM4E (1.00) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL692741 0.98 KDM4E (0.96) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL10464107 0.98 KDM4E (0.96) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL28363784 0.98 KDM4E (0.96) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL28405012 0.87 KDM4E (0.76) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL28536949 0.87 KDM4E (0.76) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL6400926 0.87 KDM4E (0.76) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL7224598 0.82 KDM4E (0.67) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL4951162 0.80 KDM4E (0.65) KDM4ECYP2C19KDM6AKDM4ACYP2C9
Deferiprone SCHEMBL9075381 0.79 KDM4E (0.63) KDM4ECYP2C19KDM6AKDM4ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9154 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144779-A1 MODIFIED RELEASE PHARMACEUTICAL FORMULATIONS COMPRISING DEFERIPRONE CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-28 US claimed
US-20260146046-A1 BICYCLIC FERROPORTIN INHIBITORS VIFOR (INTERNATIONAL) AG (CH) 2026-05-28 US claimed
CN-122080099-A Amphiphilic nicotinamide adenine dinucleotide conjugate, nano micelle and application thereof 2026-05-26 CN claimed
CN-121628980-B Quantum dot synthesized by cell in-situ programming, and preparation method and application thereof 南开大学 2026-05-22 CN claimed
EP-4097881-B1 COMMUNICATION DEVICES AND METHODS FOR ITERATIVE CODE DESIGN HUAWEI TECH CO LTD (CN) 2026-05-20 EP claimed
EP-3364967-B1 FERROPORTIN INHIBITORS VIFOR INT AG (CH) 2026-05-20 EP claimed
WO-2026098092-A1 MOTOR-RELATED ELECTROENCEPHALOGRAPHIC SIGNAL SOURCE LOCALIZATION METHOD AND SYSTEM BASED ON MNE-GAN 东南大学 2026-05-15 WO claimed
US-20260132772-A1 PANORAMIC STITCHING METHOD FOR INFRARED IMAGES OF WIND TURBINE BLADE, DEVICE, STORAGE MEDIUM, AND PRODUCT HUNAN UNIV (CN) 2026-05-14 US claimed
EP-4739300-A1 MODULATORS OF IRON METABOLISM FOR TREATING CONDITIONS ASSOCIATED WITH CONE PHOTORECEPTOR DEGENERATION SORBONNE UNIVERSITE (FR) 2026-05-13 EP claimed
US-20260130112-A1 ORGANIC ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2026-05-07 US claimed
WO-1990003840-A1 METHOD AND APPARATUS FOR CONTINUOUS CHEMICAL REACTIONS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1990-04-19 WO claimed
US-4840958-A Novel 3-hydroxypyrid-2-ones and 3-hydroxyprid-4-ones useful in treating patients having a toxic concentration of iron NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1989-06-20 US claimed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP claimed
EP-0093498-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING N-SUBSTITUTED-3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-11-26 EP claimed
EP-0094149-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING A COMPLEX OF IRON WITH N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1986-09-10 EP claimed
US-4550101-A Iron complexes of hydroxy pyridones useful for treating iron deficiency anemia NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-10-29 US claimed
EP-0159194-A2 Iron 3-hydroxypyrone or 3-hydroxypyridone complexes and pharmaceutical compositions containing them NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-10-23 EP claimed
EP-0145228-A1 Pharmaceutical compositions NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1985-06-19 EP claimed
EP-0094149-A2 Pharmaceutical compositions containing a complex of iron with N-substituted 3-hydroxypyrid-2-one or -4-one derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-11-16 EP claimed
EP-0093498-A2 Pharmaceutical compositions containing N-substituted-3-hydroxypyrid-2-one or -4-one derivatives NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1983-11-09 EP claimed